Heart & Circulation

Heart & Circulation Evidence Ranking

Within this category, verdicts with higher evidence scores appear first. Verdicts without a score stay lower in the same list.

• A 88 Oat beta-glucan x Blood cholesterol improvement (LDL-C and total cholesterol)
  Whether enough oat beta-glucan with preserved viscosity and molecular weight is consumed, usually at least 3 g/day, largely determines the effect;... · View verdict →
• B 74 Potassium x Blood pressure
  Increased potassium intake has repeated RCT evidence for blood pressure reduction, but the reduction in clinical events in salt-substitution studie... · View verdict →
• C 59 Red yeast rice (monacolin K, red yeast rice) x Cholesterol improvement
  Standardized red yeast rice with sufficient monacolin K lowers LDL-C, but the evidence is centered on blood-lipid surrogate markers and product/saf... · View verdict →
• C 55 Garlic (including allicin and aged garlic extract) x Blood pressure and cholesterol
  Blood pressure shows repeated small reductions in RCTs and meta-analyses of hypertensive groups, but cholesterol has a negative large independent R... · View verdict →
• D 36 Niacin (vitamin B3) x Cholesterol and lipids
  Niacin changes lipid surrogate markers, but the primary endpoint of major cardiovascular events was null in large RCTs on a statin background, and... · View verdict →
• D 34 Nattokinase (nattokinase, fibrinolytic enzyme derived from Bacillus subtilis natto) x Blood clots and blood circulation
  There are coagulation and peripheral-blood-flow surrogate-marker signals from small short-term studies, but clinical effects on thrombosis and bloo... · View verdict →
• C score not listed Omega-3 (EPA/DHA) x cardiovascular and blood-flow improvement
  The evidence is conflicting or limited. · View verdict →
• C score not listed Coenzyme Q10 (ubiquinone/ubiquinol) x antioxidant and blood-pressure improvement
  The evidence is conflicting or limited. · View verdict →
• D score not listed Policosanol (sugarcane-derived) x LDL cholesterol improvement
  Human evidence is insufficient or was not confirmed in key trials. · View verdict →