Energy & Fatigue

Energy & Fatigue Evidence Ranking

Within this category, verdicts with higher evidence scores appear first. Verdicts without a score stay lower in the same list.

• C 55 Octacosanol x fatigue and endurance
  Endurance has small exercise-time signals, but fatigue is mainly inferred from surrogate indicators and exercise performance, and most studies are... · View verdict →
• C 50 B-complex vitamins x Fatigue
  In general fatigue without deficiency, the key limitation is that the evidence is not independently replicated proof of a B-vitamin-specific effect... · View verdict →
• C 48 Taurine x Fatigue and vitality
  For everyday fatigue, direct RCT evidence is insufficient and the representative direct fatigue RCT was negative; the small signal for exercise dur... · View verdict →
• C 47 Schisandra chinensis (schisandra) x Fatigue, liver, and antioxidant effects
  For fatigue, liver, and antioxidant claims, human RCT signals exist, but they center on surrogate markers such as strength, lactate, ALT/AST, and o... · View verdict →
• C 46 Rhodiola (Rhodiola rosea) x Fatigue and stress
  Positive RCTs exist, but most are small, tied to specific standardized extracts and products, and a rigorous independent RCT was negative, so indep... · View verdict →
• C 46 Cordyceps (including C. militaris, C. sinensis/Cs-4, and Cordyceps mycelium culture extract) x Vitality, immunity, and exercise
  For immunity, NK/IgA surrogate markers are positive but URI reduction failed; exercise/vitality evidence is small, combination-product, and mixed,... · View verdict →
• C 46 Vitamin B12 (cobalamin) x Fatigue and anemia
  There is evidence for B12-deficiency anemia, but fatigue-recovery claims in normal B12 status are negative or insufficient. · View verdict →
• C 42 Arginine (L-arginine) x fatigue and vitality
  The core assumption is that blood-flow, ammonia, and exercise-performance surrogate indicators lead to perceived fatigue and everyday vitality, but... · View verdict →
• C 42 Iron (for non-deficient ordinary people) x Fatigue
  The positive evidence comes from correcting deficiency or low ferritin, and cannot be directly extrapolated to fatigue improvement in non-deficient... · View verdict →