CHAMGAP
FOOD & SUPPLEMENT BUNDLE

Foods and supplements claimed to help joints and bones

54 of them, ranked by strength of evidence. Only 2 reach grade A or B.

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At a glance

54 foods and supplements marketed for joints and bones, each graded one by one against clinical trial evidence. Grade spread: B 2 · C 32 · D 13 · F 3. Only 2 reach grade A or B.

The grade measures how strong the evidence is, not how good something is for you. Grade A means independent research groups replicated a reduction in real clinical events in humans; grade F means well-designed trials established there is no effect. See Methodology.

02

Claimed to help joints and bones — strongest evidence first

Within a grade, higher scores come first; verdicts without a score sit at the bottom. Follow a name to see its trials, evidence, and limits.

B 70 Vitamin D, bone-health axis Calcium absorption, prevention of osteomalacia, and reduction of fracture risk
B 62 Avocado-soybean unsaponifiables (ASU) Improvement of knee osteoarthritis pain and function
C 55 Vitamin K2 (MK-7, menaquinone-7) Bone health and vascular calcification/calcium metabolism
C 54 Rosehip (Rosa canina) Joints (osteoarthritis) and antioxidant
C 54 Chrysanthemum zawadskii extract (GCWB106) Joint and cartilage health and improvement of knee pain
C 54 Whole chilies and sweet peppers Lower odds of prevalent sarcopenia
C 51 Cetyl myristoleate complex (CMO and cetylated fatty acids) Improved knee-joint pain and function
C 50 MSM (methylsulfonylmethane) joint pain and function improvement
C 50 Boswellia serrata (frankincense) joint inflammation and pain relief
C 50 Collagen (hydrolyzed/UC-II) joint and bone health
C 50 Gelatin Joints, skin, and hair
C 50 Natural eggshell membrane (NEM) Improvement of knee-joint pain, stiffness, and function
C 50 Burdock-root decoction tea Knee osteoarthritis pain and function
C 50 Ground sesame seeds, 40 g/day Improved knee osteoarthritis pain and function
C 50 Vitamin D3 50,000 IU taken with a meal containing zero or 30% of energy from fat Higher plasma vitamin D3 concentrations 10 to 14 hours after dosing
C 48 Undenatured type II collagen (UC-II) Joint pain, function, and flexibility
C 48 Curcumin (turmeric, curcumin/turmeric) Anti-inflammatory and joint health
C 48 Lilium lancifolium extract powder Improvement of joint discomfort and function
C 48 SAMe (S-adenosyl-L-methionine; ademetionine) Improvement of osteoarthritis pain and function
C 48 Poly-gamma-glutamic acid (γ-PGA; Bacillus-fermented natto polymer) Enhanced calcium absorption and bone health
C 47 Devil's claw root (Harpagophytum procumbens) Relief of osteoarthritis and low-back pain
C 46 Prunes (dried plums) Maintenance of postmenopausal bone density and prevention of osteoporosis and fractures
C 46 Calcium fructoborate, a branded boron ingredient sold as FruiteX-B Improvement of knee-joint pain and function
C 46 One to two drinks/day, defined as beer 356 mL, wine 118 mL, or spirits 42 mL Maintained bone density and prevention of osteoporosis or fractures
C 45 Calcium (supplement) Bone health, maintenance of bone mineral density, and fracture prevention
C 44 White willow bark extract Relief of osteoarthritis pain
C 43 Tart cherry concentrate (Prunus cerasus) Reduction of uric acid and prevention of gout flares
C 42 Milk basic protein (MBP) Maintenance of bone mineral density and suppression of bone resorption
C 42 Taheebo extract (Tabebuia avellanedae, Tabetri®) Joint and cartilage health and knee discomfort
C 41 Angelica decursiva leaf extract Improvement of joint discomfort and function
C 41 L-leucine (a branched-chain essential amino acid sold as a single-ingredient supplement) Improved muscle mass, grip strength, and walking function in older adults with sarcopenia
C 40 Boron Bones, joints, and hormones
C 40 Cat's claw (Uncaria tomentosa or Uncaria guianensis, dietary supplement) Relief of pain and inflammation in osteoarthritis and rheumatoid arthritis
C 40 Cissus quadrangularis (a Vitaceae plant-extract supplement) Faster clinical and radiographic fracture union with less pain and swelling when added to fracture fixation
D 35 Chondroitin (chondroitin, mainly chondroitin sulfate) Claims for joint and cartilage health, improvement of osteoarthritis pain and function, and maintenance of joint space
D 34 Glucosamine joint (knee) pain and function improvement
D 34 Aquamin marine-algae multimineral from Lithothamnion Increased bone mineral density and prevention of fractures
D 34 Mixed intake of lean and oily fish Prevention of incident rheumatoid arthritis
D 34 Nonfermented milk without complete separation by fat content Prevention of total and hip fractures in adults
D 32 Glucosamine sulfate (oral joint supplement and medicine in some countries) Improvement of chronic low back pain and disability associated with degenerative lumbar disease
D 31 Choline-stabilized orthosilicic acid (ch-OSA, a bioavailable silicon complex sold in supplements such as BioSil) Improved bone formation and femoral bone density when added to calcium and vitamin D in women with osteopenia
D 30 At least four 150-mL cups of coffee daily, 600 mL or more, or caffeine above 330 mg/day Prevention of osteoporotic fractures in women
D 30 Vitamin D3 1,200 IU daily in healthy term infants Greater bone strength at 24 months than standard 400 IU daily
D 28 Green-lipped mussel oil (New Zealand green-lipped mussel) joint pain relief
D 28 Whole full-fat yogurt Improved bone-turnover markers
D 28 Uncooked lactobacilli-rich vegan diet Improved rheumatoid-arthritis activity and symptoms
D 25 Shark cartilage Joints and anticancer effects
F 18 Glucosamine (a prescription product or dietary supplement) Improvement of chronic low-back pain and disability in degenerative lumbar osteoarthritis
F 18 Vitamin D3 (cholecalciferol, a fat-soluble vitamin sold nonprescription and as a supplement) Improved pain and function and reduced cartilage loss in symptomatic knee osteoarthritis
F 5 Vitamin D3, or cholecalciferol Prevention of falls in community-dwelling older adults without vitamin D deficiency
? score not listed Achyranthes root Joints
? score not listed Strontium citrate Increased bone mineral density and fracture prevention
? score not listed Rhus toxicodendron 30C homeopathic product Relief of joint pain, stiffness, and weather-related muscle pain
? score not listed Sagol-guk or gomtang, a soup made by prolonged simmering of beef bones Reduced osteoarthritis pain and improved physical function
03

Not swallowed — applied, inhaled, held in the mouth, worn, or performed on the body (8)

Same claims, but these are not taken by mouth: rubbed on the skin, breathed in, chewed or rinsed and spat out, worn on the body, or performed as a procedure such as acupuncture or cupping. A different route into the body, so they are listed separately.

C 56 Acupuncture, primarily manual needle acupuncture Clinically meaningful improvement in pain and physical function from knee osteoarthritis
C 54 Dry needling (insertion of an unmedicated needle into myofascial trigger points) Reduced morning first-step and foot pain in plantar fasciitis
C 46 Pyrrolizidine-alkaloid-reduced comfrey root extract ointment, Kytta-Salbe f Reduced acute nonspecific upper or lower back pain
C 44 Dry needling (a physical-therapy adjunct inserting a needle into myofascial trigger points without injecting medicine) Reduction of chronic nonspecific neck muscle pain and disability
D 30 Emu oil (topical animal-derived oil from emu fat, sold as a cosmetic or wellness product) Relief of knee or hand arthritis and joint pain
D 28 Cushioned insoles containing static bipolar magnets Relief of plantar heel pain
F 10 Copper bracelet (skin-worn device) Relief of pain and inflammation in rheumatoid arthritis
F 10 Static magnetic bracelet (magnetic health bracelet) Improved pain, stiffness, and function in knee or hip osteoarthritis
04

Claimed to harm joints and bones (1)

Here a higher grade means the harm is better established — the opposite direction from the table above. A low grade means the claim of harm rests on weak evidence.

C 54 Repeated consumption of carbonated soft drinks, including cola Lower bone mineral density or increased fracture
05

What does have evidence for joints and bones

Not foods or supplements: drugs and procedures graded A or B. Chamgap recommends nothing. It only shows where the evidence is strong. Any treatment decision belongs with your doctor.

A 88 Zoledronic acid (intravenous bisphosphonate, Aclasta, prescription) Prevention of vertebral, hip, and nonvertebral fractures in patients with osteoporosis
A 86 Risedronate sodium (oral bisphosphonate, Actonel, prescription drug) Prevention of vertebral and hip fractures in postmenopausal osteoporosis
A 86 Tai Ji Quan: Moving for Better Balance (therapeutic balance-exercise program) Reduction of falls in community-dwelling older adults at high risk
A 86 Otago Exercise Programme (individually prescribed home balance, strength, and walking exercise) Reduction of actual falls among community-dwelling older adults
B 79 Denosumab (RANKL inhibitor, Prolia, prescription medicine) Reduction of vertebral, hip, and nonvertebral fractures in postmenopausal women with osteoporosis
B 79 Alendronate (bisphosphonate; Fosamax; prescription) Prevention of vertebral, hip, and nonvertebral fractures in postmenopausal osteoporosis with a prior fragility fracture
B 79 Topical diclofenac (Voltaren Emulgel, nonprescription medicine) Reduced pain and improved function in knee osteoarthritis
B 79 Methotrexate (folate-antagonist conventional synthetic disease-modifying antirheumatic drug and prescription medicine) First-line disease control and inhibition of joint-damage progression in disease-modifying-antirheumatic-drug-naive moderate-to-high-activity rheumatoid arthritis
B 78 Romosozumab (sclerostin-inhibiting antibody, Evenity, prescription medicine) Prevention of vertebral, hip, and clinical fractures in postmenopausal women at high fracture risk
B 77 Teriparatide (PTH analog and bone-forming agent, Forteo, prescription) Prevention of new vertebral and nonvertebral fractures in patients with osteoporosis at high fracture risk
B 77 Raloxifene (prescription selective estrogen-receptor modulator, or SERM) Reduced risk of new vertebral fractures in postmenopausal women with osteoporosis
B 76 Etoricoxib 30 mg, a prescription selective COX-2 nonsteroidal anti-inflammatory drug Reduced pain and improved physical function in symptomatic knee or hip osteoarthritis
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How to read this list

A grade of C or D does not mean "do not take it." It means the evidence is not yet strong enough to promise the effect. Equally, A or B does not mean it works for everyone.

Chamgap sells nothing and takes no advertising. See all Joints & Bones verdicts.