Germinated fermented soybean extract,
does it really help with Relief of menopausal symptoms in women?
research showsGerminated fermented soybean extract is registered in South Korea as individually recognized ingredient No. 2022-8, and KCT0002961 preregistered a 100-participant, 12-week, multicenter, randomized, double-blind, placebo-controlled trial. No results paper, effect size, attrition details, or full funding information is public, so verification is limited and the verdict is the lowest C at 40 points.
ads claimMarketing may use coumestrol and regulatory recognition to imply proven hormone balance or comprehensive menopause relief. Public evidence does not permit evaluation of symptom-specific effect sizes, responder rates, or long-term durability.
Useful facts when choosing a product
- This is a specific extract powder made by germinating and fermenting domestically developed soybeans to contain coumestrol.
- MFDS recognition No. 2022-8 states the function as support for women's health during menopause and a daily intake of 1 g.
- Korean product labels confirm use of germinated fermented soybean extract powder, but some products include it only as a secondary ingredient, so the label must distinguish a functional main ingredient from an auxiliary ingredient.
- KCT0002961 preregistered a HUBIO-sponsored, target-n=100, 12-week, multicenter, randomized, double-blind, placebo-controlled trial, but results are not public.
What the research actually shows
Food Safety Korea lists germinated fermented soybean extract as individually recognized ingredient No. 2022-8, with the function 'may help women's health during menopause' and a daily intake of 1 g. Trial registry KCT0002961 preregistered a HUBIO-sponsored, target-n=100, 12-week, multicenter, randomized, double-blind, placebo-controlled trial. Registration and preregistration establish that a trial exists, but verification of human efficacy is limited because no results paper, effect size, attrition details, or full funding information is public. The ovariectomized-animal and cellular estrogen-receptor data in patent WO2014182044A1 are not human efficacy evidence.
Why this is classified as C (40)
Registration No. 2022-8 and preregistration KCT0002961 confirm that a human trial exists for the exact ingredient. Public results, effect size, attrition details, full funding information, and independent replication are absent, so the rating is the lowest C at 40 points.
Counterpoint. Registration and preregistration establish trial existence, so the ingredient is not treated as evidence-free. They do not establish efficacy without public human results.
Rejudgment record. Reassessment (cross-check reflected) — The reassessment reflects individual recognition No. 2022-8 and the existence of preregistered trial KCT0002961 while limiting confidence for absent public results, effect sizes, attrition details, full funding information, and independent replication
Cross-check — Codex and Claude
Evidence Table
| Study | Design | Sample | Funding | Endpoint | Result | Weight |
|---|---|---|---|---|---|---|
| Study 1 | Individually recognized functional-ingredient registration | HUBIO recognized ingredient | Support for women's health during menopause; daily intake 1 g/day | Germinated fermented soybean extract is registered as individually recognized ingredient No. 2022-8. Registration indicates a submitted dossier but is not itself a public human result. | Indirect, unpublished results | |
| KCT0002961 | Preregistered multicenter randomized double-blind placebo-controlled trial | 12 | Sponsor: HUBIO | Efficacy and safety for menopausal symptoms | The design and target sample were registered, but no results paper, effect size, or attrition details are public. | Indirect, unpublished results |
Receipt — 2 References
All 2 cited sources were verified for existence at the original page (as of 2026-07-15).
Reviewed and approved: Chamgap Editorial Team · Approval date: 2026-07-15 · Corrections: none
Cite this verdict
[Chamgap] Germinated fermented soybean extract × Relief of menopausal symptoms in women — Evidence Grade C·40. 2 cited sources checked. Source: https://health-receipt.pages.dev/en/verdicts/womens/germinated-fermented-soybean-extract/ · CC BY 4.0CC BY 4.0 — free to use with attribution; do not distort grades, numbers, or verdict meaning.
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